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OCR: d other Stress also causes the release of ACTH none and pituitary hormones (such as growth ho ma) prolactin). Chronic stress (anxiety or tr evels and produces prolonged elevation of ACTI the thus an increase in cortisol secretion. I investigation of patients with suspecte eous to be hypopituitarism, it is clinically advant ng able to provoke ACTH release by produ of the controlled hypoglycaemia. The integri thus be hypothalamic-pituitary-adrenal axis m entration examined by measuring the plasma co other of cortisol (Fig. 7.11 ) and, if necessary, tress, e.g. pituitary hormones that are released b prolactin and growth hormone.